The drying of FD-20 drug freeze-drying machine is basically carried out at a temperature below 0 ℃, that is, in the frozen state of the product, until later, in order to further reduce the residual moisture content of the product, the product is raised to a temperature above 0 ℃, but generally not exceeding 40 ℃.
1、 Product Introduction
Pharmaceutical freeze-drying machines are widely used in fields such as medicine, pharmaceuticals, biological research, and chemical engineering. Drying is one of the methods to keep substances from rotting. There are many drying methods, such as sun drying, boiling drying, drying, spray drying and vacuum drying. But these drying methods are all carried out at temperatures above 0 ℃ or higher. The products obtained from drying generally have a reduced volume and a harder texture. Some substances have undergone oxidation, and most of the volatile components have been lost. Some heat sensitive substances, such as proteins and vitamins, may undergo denaturation. Microorganisms will lose their biological vitality, and dried substances are not easily soluble in water. Therefore, the dried product has significant differences in appearance compared to before drying. The freeze-drying method is different from the above drying methods. The drying of the product is basically carried out at a temperature below 0 ℃, that is, in the frozen state of the product, until later, in order to further reduce the residual moisture content of the product, the product is raised to a temperature above 0 ℃, but generally not exceeding 40 ℃.
2、 Product features:
1. The vacuum system adopts a combination of water seal pump and oil seal pump. In the initial stage, the air is quickly pre pumped by a high-power oil seal pump group to maintain the working vacuum, and a low-power Roots water seal pump group is used. It can reduce energy consumption, and at the same time, the water seal pump can extract water vapor, avoiding the disadvantages of oil seal pumps due to poor drainage performance, water vapor causing emulsification and deterioration of pump oil, and resulting in unstable vacuum degree in the system.
2. Heating is a closed water circulation system, which uses a three-way regulating valve to automatically adjust the heat supply of the water circulation system, control the temperature of the heating plate, and automatically regulate the pressure with nitrogen to ensure that the working temperature of the hot water reaches 120 ℃.
3. Adopting rear and bottom mounted water trap, compared with split external cold trap, the passage is shorter, the resistance is smaller, the water vapor passage is designed smoothly, the water capture is uniform, and the water capture efficiency is improved. The water trap adopts the ammonia single cycle refrigeration method, which is more stable and easy to operate compared to the commonly used liquid supply method. Small and medium-sized equipment can use Freon refrigeration, with the supply flow rate adjusted by an expansion valve.
Drug freeze-drying machine
3、 Product advantages:
1. Freeze drying is carried out at low temperatures, making it particularly suitable for many heat sensitive substances. Proteins, microorganisms, and the like will not undergo denaturation or lose their biological vitality. Therefore, it has been widely used in medicine.
2. When dried at low temperatures, the loss of some volatile components in the substance is minimal, making it suitable for drying some chemical products, drugs, and food.
3. During the freeze-drying process, the growth of microorganisms and the action of enzymes cannot be carried out, so the original characteristics can be maintained.
4. Due to drying in a frozen state, the volume remains almost unchanged, maintaining the original structure and preventing concentration.
5. After drying, the substance quickly dissolves and almost immediately returns to its original form when water is added.
6. Due to the drying process being carried out under vacuum with very little oxygen, some easily oxidizable substances are protected.
7. Drying can remove more than 95-99% of moisture, allowing the dried product to be stored for a long time without deterioration.